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Estradiol is a form of estrogen. It is a female hormone which is typically given to women who no longer produce the proper amount of this hormone. It is used to reduce menopause symptoms (for example, hot flashes and vaginal dryness), to prevent bone loss (osteoporosis) in people at high risk, or possibly even to treat certain cancers in men and women (e.g., certain types of metastatic breast cancer). It may also be used to treat other conditions as determined by a doctor. Like other sex steroids, Estradiol is derived from cholesterol.

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Some of Estradiol's main functions and effects are:
- Breast development and maintenance
- Adding fat to breasts, hips, thighs during puberty
- Improving bone strength and density
- Accelerating bone maturation and bringing epiphyses to closure, completing growth
- Growth of the uterus
- Development of the endometrial lining to a thickness necessary to support pregnancy and menstruation
- Thinning of cervical mucus at ovulation
- Promoting and maintaining vaginal mucosal thickness and secretions
- Serving as the primary feedback to the brain of sex hormone levels in both males and females.
- Participating in triggering ovulation
- Preservation of egg cells
- Enabling spermatogenesis

Estradiol Side Effects
Estradiol may cause a feeling of or actually being sick, stomach cramps, enlarged or tender breasts, water retention, PMS-type symptoms, bloating, weight changes, skin rashes, depression, headache, dizziness generalised itching, patches of discoloured skin, nose bleeds, inflammation of existing varicose veins, changes in sexual desire, or leg cramps. If you are taking this medication and notice other side effects and/or if any are particularly troubling or bothersome, be sure to contact a Physician immediately.

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